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KMID : 0914820160160020115
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Journal of the Korean Gastric Cancer Association
2016 Volume.16 No. 2 p.115 ~ p.119
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A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis
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Rim Chang-Bum
Lee Jung-Ae
Gong Soo-Jung
Kang Dong-Wook
Yang Hee-Bum
Han Hyun-Young
Kim Nae-Yu
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Abstract
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We report the case of a patient with gastric adenocarcinoma with multiple liver metastases. This patient showed complete remission for more than 68 months after S-1/cisplatin combination chemotherapy and radical total gastrectomy. The patient, a 63-year-old man, presented with dyspepsia and difficulty in swallowing. Endoscopic findings showed a huge ulcero-infiltrative mass at the lesser curvature of the mid-body, extending to the distal esophagus. Biopsy revealed a poorly differentiated tubular adenocarcinoma. An abdominal computed tomography scan demonstrated multiple hepatic metastases. S-1/cisplatin combination chemotherapy was initiated, and following completion of six cycles of chemotherapy, the gastric masses and hepatic metastatic lesions had disappeared on abdominal computed tomography. Radical total gastrectomy and D2 lymphadenectomy combined with splenectomy were performed. The patient underwent three cycles of S-1/cisplatin combination chemotherapy followed by tegafur-uracil therapy for 1 year. He remained in complete remission for more than 68 months after surgery.
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KEYWORD
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Gastric cancer, Liver metastasis, Gastrectomy, S-1, Cisplatin, Cisplatin
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